In:
ChemistrySelect, Wiley, Vol. 3, No. 5 ( 2018-02-07), p. 1609-1614
Kurzfassung:
The present work involves the synthesis of Benzothiazole capped triazole‐silane (3) by ‘Click Silylation’ and its immobilization onto silica surface. This new silane is characterised by IR, 1H, 13C spectroscopy. TGA, TEM and SEM were the evidence for its adsorption at silica surface. The anti‐parasitic, anti bacterial and anti oxidant activity of synthesised compounds was evaluated. The results shows that nanoparticle of silane displayed more significant activity as compared to benzothiazole derived silane (3) against G. lamblia, T. vaginalis, various bacterial strains (E.coli, Bacillus subtillus, Staphylococcus aureus, Vibrio cholera) and showed potential anti‐oxidant activity. Further Molecular docking study was performed to analyse the binding manner and enzyme inhibitory activity of compound‐ 3 with β‐glucuronidase.
Materialart:
Online-Ressource
ISSN:
2365-6549
,
2365-6549
DOI:
10.1002/slct.201703017
Sprache:
Englisch
Verlag:
Wiley
Publikationsdatum:
2018
ZDB Id:
2844262-3
