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Preferential uptake of intravenously administered hyaluronidase (Hyalosidase) by damaged rat myocardium

Earnshaw, Julia S. ; Peh, Kheng H. ; Dodgson, Kenneth S. ; [weitere]

Portland Press Ltd. ; 1985

In: Bioscience Reports Vol. 5, No. 4 ( 1985-04-01), p. 329-334

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In: Bioscience Reports, Portland Press Ltd., Vol. 5, No. 4 ( 1985-04-01), p. 329-334

Kurzfassung: The induction of myocardial infarction in rats by ligation of the left – anterior coronary artery was confirmed by measurement of increased plasma levels of creatine kinase, aspartate aminotransferase and lactate dehydrogenase. Using this model system it has been established that intravenous administration of 12SI-labelled hyaluronidase to rats resulted in a preferential uptake of the enzyme by damaged myocardium as compared to normal heart tissue.

Materialart: Online-Ressource

ISSN: 0144-8463 , 1573-4935

URL: Article

DOI: 10.1007/BF01116905

Sprache: Englisch

Verlag: Portland Press Ltd.

Publikationsdatum: 1985

ZDB Id: 2014993-1

SSG: 12