In:
Journal of Industrial Microbiology and Biotechnology, Oxford University Press (OUP), Vol. 41, No. 3 ( 2014-03-01), p. 555-561
Kurzfassung:
The cellular response of Blakeslea trispora to oxidative stress induced by H2O2 in shake flask culture was investigated in this study. A mild oxidative stress was created by adding 40 μm of H2O2 into the medium after 3 days of the fermentation. The production of β-carotene increased nearly 38 % after a 6-day culture. Under the oxidative stress induced by H2O2, the expressions of hmgr, ipi, carG, carRA, and carB involving the β-carotene biosynthetic pathway all increased in 3 h. The aerobic metabolism of glucose remarkably accelerated within 24 h. In addition, the specific activities of superoxide dismutase and catalase were significantly increased. These changes of B. trispora were responses for reducing cell injury, and the reasons for increasing β-carotene production caused by H2O2.
Materialart:
Online-Ressource
ISSN:
1476-5535
,
1367-5435
DOI:
10.1007/s10295-013-1392-1
Sprache:
Englisch
Verlag:
Oxford University Press (OUP)
Publikationsdatum:
2014
ZDB Id:
1482484-X
SSG:
12