In:
Magnetic Resonance Materials in Physics, Biology and Medicine, Springer Science and Business Media LLC, Vol. 34, No. 5 ( 2021-10), p. 667-676
Abstract:
There is a tendency for reducing TR in MRI experiments with multi-band imaging. We empirically investigate its benefit for the group-level statistical outcome in task-evoked fMRI. Methods Three visual fMRI data sets were collected from 17 healthy adult participants. Multi-band acquisition helped vary the TR (2000/1000/410 ms, respectively). Because these data sets capture different temporal aspects of the haemodynamic response (HRF), we tested several HRF models. We computed a composite descriptive statistic, H, from β ’s of each first-level model fit and carried it to the group-level analysis. The number of activated voxels and the t value of the group-level analysis as well as a goodness-of-fit measure were used as surrogate markers of data quality for comparison. Results Increasing the temporal sampling rate did not provide a universal improvement in the group-level statistical outcome. Rather, both the voxel-wise and ROI-averaged group-level results varied widely with anatomical location, choice of HRF and the setting of the TR. Correspondingly, the goodness-of-fit of HRFs became worse with increasing the sampling frequency. Conclusion Rather than universally increasing the temporal sampling rate in cognitive fMRI experiments, these results advocate the performance of a pilot study for the specific ROIs of interest to identify the appropriate temporal sampling rate for the acquisition and the correspondingly suitable HRF for the analysis of the data.
Type of Medium:
Online Resource
ISSN:
0968-5243
,
1352-8661
DOI:
10.1007/s10334-021-00918-z
Language:
English
Publisher:
Springer Science and Business Media LLC
Publication Date:
2021
detail.hit.zdb_id:
1502491-X
SSG:
11
