In:
FEBS Letters, Wiley, Vol. 426, No. 3 ( 1998-04-24), p. 314-318
Abstract:
The vesicle to micelle transition which results in the interaction of the Triton X‐100 surfactant with phosphatidylcholine vesicles was studied by means of dynamic light scattering (at different reading angles) and by freeze‐fracture electron microscopy techniques. Vesicle solubilization was produced by the direct formation of mixed micelles without the formation of complex intermediate aggregates. Thus, vesicle to micelle transformation was mainly governed by the progressive formation of mixed micelles within the bilayer. A subsequent separation of these micelles from the liposome surface (vesicle perforation by the formation of surfactant‐stabilized holes on the vesicle surface) led to a complete solubilization of liposomes.
Type of Medium:
Online Resource
ISSN:
0014-5793
,
1873-3468
DOI:
10.1016/S0014-5793(98)00363-9
Language:
English
Publisher:
Wiley
Publication Date:
1998
detail.hit.zdb_id:
212746-5
detail.hit.zdb_id:
1460391-3
SSG:
12