In:
FEBS Letters, Wiley, Vol. 585, No. 18 ( 2011-09-16), p. 2876-2882
Abstract:
► The Ku70–Ku80 heterodimer (Ku) is a critical component of the NHEJ pathway. ► Ku removal from DNA is an important aspect of pre‐ and post‐repair mechanisms. ► Ku80 can be removed from DNA via its K48‐linked poly‐ubiquitylation. ► Ubiquitylation, followed by protein unfolding, is emerging as a general mechanism for the release of DNA‐bound proteins.
Type of Medium:
Online Resource
ISSN:
0014-5793
,
1873-3468
DOI:
10.1016/j.febslet.2011.05.046
Language:
English
Publisher:
Wiley
Publication Date:
2011
detail.hit.zdb_id:
1460391-3
SSG:
12