In:
FEBS Open Bio, Wiley, Vol. 5, No. 1 ( 2015-01), p. 219-225
Abstract:
We modeled the mitochondrial disease MELAS by generating patient‐specific iPS cells. MELAS‐iPS cells show a wide variety of heteroplasmy levels. MELAS‐iPS cells with high heteroplasmy levels showed impaired complex I activity.
Type of Medium:
Online Resource
ISSN:
2211-5463
,
2211-5463
DOI:
10.1016/j.fob.2015.03.008
Language:
English
Publisher:
Wiley
Publication Date:
2015
detail.hit.zdb_id:
2651702-4