In:
FEBS Open Bio, Wiley, Vol. 5, No. 1 ( 2015-01), p. 779-788
Abstract:
An alpaca‐derived γ‐H2AX nanobody was generated. γ‐H2AX chromobody was able to bind and precipitate phosphorylated H2AX peptide. γ‐H2AX chromobody could be produced in bacterial as well as mammalian cells. Alternative epitope recognition by γ‐H2AX chromobody was induced by ectopic XRCC1. Accessibility of γ‐H2AX chromobody was hindered by MDC1 masking in vivo .
Type of Medium:
Online Resource
ISSN:
2211-5463
,
2211-5463
DOI:
10.1016/j.fob.2015.09.005
Language:
English
Publisher:
Wiley
Publication Date:
2015
detail.hit.zdb_id:
2651702-4