In:
Molecular Oncology, Wiley, Vol. 10, No. 1 ( 2016-01), p. 157-165
Abstract:
The sensitivity of ctDNA assays to detect metastatic melanoma were compared to LDH. 31 patients with unresectable stage IIIC/IV melanoma were studied. Droplet digital PCR assays detecting BRAF and NRAS mutations were used. ctDNA is more sensitive than LDH in detecting metastatic disease. ctDNA is a sensitive indicator of disease progression, including brain metastases.
Type of Medium:
Online Resource
ISSN:
1574-7891
,
1878-0261
DOI:
10.1016/j.molonc.2015.09.005
Language:
English
Publisher:
Wiley
Publication Date:
2016
detail.hit.zdb_id:
2322586-5