In:
British Journal of Nutrition, Cambridge University Press (CUP), Vol. 104, No. 10 ( 2010-11-28), p. 1514-1522
Kurzfassung:
The objective of the present study was to evaluate the effect of a paediatric tube feed supplemented with a multifibre mixture on the gut microbiota and nutritional and micronutrient status of children on long-term enteral nutrition (EN). A randomised, controlled, double-blind, cross-over trial (2 × 3 months) with a washout period of 1 month was carried out. Twenty-seven children (80 % neurologically impaired) aged 11·9 ( sd 3·9) years, on long-term EN (4·8 ( sd 3·9) years) were recruited. The analyses of the children's faecal pH, microbiota along with anthropometric measures, bowel movements and markers of blood micronutrient status were made. Twenty children completed the study. A significant increase in the proportion of stool bifidobacteria (+16·6 %, P 〈 0·05) was observed during the multifibre period than during the fibre-free period, together with a significant reduction in stool pH ( P 〈 0·001). Stool frequency and consistency as well as growth did not differ between the two periods. There was a significant increase ( P 〈 0·05) in plasma ferritin at the end of the fibre-free period, but plasma ferritin levels remained within normal ranges during both periods. No diet effects on other blood parameters were observed. In conclusion, addition of a multifibre mixture with prebiotic components to paediatric EN is well tolerated, promotes bifidobacteria and reduces stool pH, indicating an improved gut health.
Materialart:
Online-Ressource
ISSN:
0007-1145
,
1475-2662
DOI:
10.1017/S0007114510002461
Sprache:
Englisch
Verlag:
Cambridge University Press (CUP)
Publikationsdatum:
2010
ZDB Id:
2016047-1
SSG:
12
SSG:
21
