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Decline of maternal antibodies to plague in Norway rats

Williams, James E. ; Eisenberg, George H. G. ; Cavanaugh, Dan C.

Cambridge University Press (CUP) ; 1977

In: Journal of Hygiene Vol. 78, No. 1 ( 1977-02), p. 27-31

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In: Journal of Hygiene, Cambridge University Press (CUP), Vol. 78, No. 1 ( 1977-02), p. 27-31

Abstract: The decline of maternal antibodies to the fraction I antigen of Yersinia pestis was investigated in newly weaned Rattus norvegicus obtained from dams vaccinated with strain EV76(51f) of Y. pestis. IHA titre decreased by 50% each 7.3 days and CF titre declined 50% each 10.0 days in young rats. An analysis of available data indicated that maternal IHA and CF antibodies could persist to 3 months of age. Therefore, positive serologic reactions in young R. norvegicus , detected in the course of serological surveys, could be the result either of active immunization after exposure to the plague bacillus or of transient passive immunization (i.e. maternal antibody).

Type of Medium: Online Resource

ISSN: 0022-1724

URL: Article

DOI: 10.1017/S0022172400055893

Language: English

Publisher: Cambridge University Press (CUP)

Publication Date: 1977

detail.hit.zdb_id: 1470211-3