In:
Pediatric Transplantation, Wiley, Vol. 7, No. s3 ( 2003-04), p. 51-55
Abstract:
Abstract: The transplantation of megadoses of haploidentical hematopoietic stem cells is for a number of children with malignant or nonmalignant diseases the only curative approach. In order to prevent severe GvHD, the removal of T lymphocytes from the stem cell graft either by positive selection of CD34 + stem cells or by negative depletion of CD3 + T lymphocytes is necessary. We present the results obtained so far by CD34 + positive selection and discuss new techniques of graft engineering which might hopefully further improve the outcome of haploidentical stem cell transplantation.
Type of Medium:
Online Resource
ISSN:
1397-3142
,
1399-3046
DOI:
10.1034/j.1399-3046.7.s3.7.x
Language:
English
Publisher:
Wiley
Publication Date:
2003
detail.hit.zdb_id:
2008614-3