In:
Scientific Reports, Springer Science and Business Media LLC, Vol. 8, No. 1 ( 2018-01-19)
Kurzfassung:
The ankle-brachial index (ABI) is a reliable diagnostic examination for peripheral arterial occlusive disease (PAOD). We previously reported CHADS 2 score was significantly correlated with PAOD. However, the association between CHA 2 DS 2 -VASc score and ABI 〈 0.9 is not evaluated in the literature. The aim of the present study was to investigate whether CHA 2 DS 2 -VASc score has a strong association with PAOD. We enrolled 1482 patients in this study. PAOD was defined as ABI 〈 0.9 in either leg. Vascular disease in CHA 2 DS 2 -VASc score was modified as vascular disease except PAOD. Of the 1482 subjects, the prevalence of ABI 〈 0.9 was 5.6%. Multivariate analysis showed that the increased age, decreased estimated glomerular filtration rate and increased modified CHA 2 DS 2 -VASc score (OR, 1.764; p 〈 0.001) were independent associated with ABI 〈 0.9. In addition, the percentage of ABI 〈 0.9 in patients with modified CHA 2 DS 2 -VASc score of 0, 1, and 〈 2 were 0%, 0.9%, and 0.7%, respectively (All 〈 1%). Our study demonstrated modified CHA 2 DS 2 -VASc score was significantly associated with ABI 〈 0.9. Calculation of modified CHA 2 DS 2 -VASc score might be useful in identifying patients with PAOD and in stratifying the risk of PAOD in non-AF patients.
Materialart:
Online-Ressource
ISSN:
2045-2322
DOI:
10.1038/s41598-018-19243-y
Sprache:
Englisch
Verlag:
Springer Science and Business Media LLC
Publikationsdatum:
2018
ZDB Id:
2615211-3
