In:
Organic & Biomolecular Chemistry, Royal Society of Chemistry (RSC), Vol. 21, No. 8 ( 2023), p. 1653-1656
Abstract:
The stereo-controlled total synthesis of (−)-domoic acid is described. The critical construction of the C1′–C2′ Z -configuration was accomplished by taking advantage of an unsaturated lactam structure. The side chain fragment was introduced in the final stages of synthesis through a modified Julia–Kocieński reaction, aiming for its efficient derivatization.
Type of Medium:
Online Resource
ISSN:
1477-0520
,
1477-0539
Language:
English
Publisher:
Royal Society of Chemistry (RSC)
Publication Date:
2023
detail.hit.zdb_id:
2097583-1
