In:
RSC Advances, Royal Society of Chemistry (RSC), Vol. 12, No. 43 ( 2022), p. 28147-28151
Abstract:
Investigation of the alkaloids from Myrioneuron effusum leads to the isolation of myrionsumamide A (1), a pair of enantiomeric alkaloids with an unprecedented tetracyclic system skeleton. These two alkaloids were separated by chiral HPLC with a ratio of 3 : 5 from the scalemic mixture. Their structures including absolute configurations were determined by NMR spectroscopy, X-ray diffraction data and ECD calculations. Both (+)-1 and (−)-1 showed antibacterial activity against Staphylococcus aureus with MIC at 7.81 μg ml −1 .
Type of Medium:
Online Resource
ISSN:
2046-2069
Language:
English
Publisher:
Royal Society of Chemistry (RSC)
Publication Date:
2022
detail.hit.zdb_id:
2623224-8
