In:
Physical Chemistry Chemical Physics, Royal Society of Chemistry (RSC), Vol. 25, No. 30 ( 2023), p. 20212-20217
Abstract:
Coumarins remain one of the most important groups of fluorescent bio-probes, thanks to their high quantum yields, moderate photostability, efficient cell permeation and low (cyto)toxicity. Herein, we introduce new 3-aminocoumarins as turn-on pH probes under strongly acidic conditions and for indicators capable of significantly improving yeast vacuolar lumen staining compared to the commercial CMAC derivatives. We present the details of the on–off switching mechanism revealed by the TD-DFT and ab initio calculations complemented by a Franck–Condon analysis of the probes’ emission profiles.
Type of Medium:
Online Resource
ISSN:
1463-9076
,
1463-9084
Language:
English
Publisher:
Royal Society of Chemistry (RSC)
Publication Date:
2023
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1476283-3
detail.hit.zdb_id:
1476244-4
detail.hit.zdb_id:
1460656-2