In:
Inorganic Chemistry Frontiers, Royal Society of Chemistry (RSC), Vol. 10, No. 17 ( 2023), p. 5144-5151
Abstract:
Combining supramolecular chemistry and bioscience, metal–organic frameworks (MOFs) built with biomolecules as ligands possess highly ordered structures and unique pores with accessible metal binding sites and rich interactions to drive molecular recognition processes. In this work, a novel purine-based MOF with chiral helical channels has been successfully constructed, named HSTC-1, which identifies H 2 O 2 with a fluorescence quenching effect. Notably, the successful encapsulation of H 2 O 2 could be observed by single-crystal X-ray diffraction. Metadynamics and density functional theory calculations reveal that the adsorption of H 2 O 2 molecules through the chiral channels induces chiral distribution of subsequent guests to form a host–guest recognition system of H 2 O 2 @HSTC-1, which slows down the oxidation of the host framework. This work provides unique insights for the construction of intelligent protection matrix materials and is of great significance in the fields of pharmacochemistry and biomedicine.
Type of Medium:
Online Resource
ISSN:
2052-1553
Language:
English
Publisher:
Royal Society of Chemistry (RSC)
Publication Date:
2023
