In:
Tierärztliche Praxis Ausgabe K: Kleintiere / Heimtiere, Georg Thieme Verlag KG, Vol. 51, No. 01 ( 2023-02), p. 15-21
Abstract:
Objectives Canine eosinophilic bronchopneumopathy (EBP) is a poorly
understood disease characterized by chronic inflammation of the lower airways. To date, factors affecting the course of the disease are largely unknown. The
objective of this study was to investigate the influence of clinical, laboratory, and environmental factors on therapeutic outcome in dogs with
EBP. Material and methods Environmental and housing conditions, course of
disease, and response to treatment were evaluated using a standardized questionnaire for owners of 29 dogs diagnosed with EBP from 3 different
veterinary referral centers in Germany. Data of diagnostic tests (hematology, radiographs, bronchoalveolar-lavage-fluid-(BALF) cytology) were retrospectively
obtained from medical records. The influence of the different factors was assessed using Fisher's-exact-test and Mann-Whitney-U- or
Kruskal-Wallis-test. Results The proportion of neutrophilic granulocytes in BALF-cytology was
significantly higher in dogs with persistent clinical signs compared to dogs that achieved clinical remission (p=0.029). Duration of clinical signs
before treatment was significantly longer in dogs with persistent clinical signs (16±12 months) compared to dogs that achieved clinical remission
(6±7 months) (p=0.017). Conclusion Early diagnosis and therapy have a decisive influence on the
success of treatment. Clinical relevance Dogs with respiratory signs suspicious for EBP should
be evaluated in a timely manner to increase the likelihood of clinical remission with an early start of therapy.
Type of Medium:
Online Resource
ISSN:
1434-1239
,
2567-5842
Language:
English
Publisher:
Georg Thieme Verlag KG
Publication Date:
2023
SSG:
22
