In:
Nuklearmedizin, Georg Thieme Verlag KG, Vol. 40, No. 01 ( 2001), p. 7-14
Abstract:
Aim: In the follow-up of patients with advanced stage thyroid cancer radioiodine scintigraphy, F-l 8-FDG PET and tumormarker hTg using stimulation with recombinant human TSH (rhTSH) were compared to the results of same diagnostic procedures during TSH-suppression or endogenous TSH-stimulation. Methods: 30 patients were investigated in hypothyroidism and after application of rhTSH regarding the serum hormone concentrations, hTg, radioiodine scans and FGD-PET scans. Results: Radioiodine avidity and FDG uptake were significantly higher in 7/30 and 3/5 patients, respectively, compared to endogenous stimulation or TSH-suppression. In about one third of patients hTg increased more than 30%. Conclusion: Our preliminary results indicate a sufficient feasibility and sensitivity of rhTSH not only in the follow-up by hTg and radioiodine scan but also in FDG-PET.
Type of Medium:
Online Resource
ISSN:
0029-5566
,
2567-6407
DOI:
10.1055/s-0038-1623986
Language:
English
Publisher:
Georg Thieme Verlag KG
Publication Date:
2001