In:
AIP Advances, AIP Publishing, Vol. 2, No. 1 ( 2012-03-01)
Kurzfassung:
The ultrashort duration of laser-driven multi-MeV ion bursts offers the possibility of radiobiological studies at extremely high dose rates. Employing the TARANIS Terawatt laser at Queen's University, the effect of proton irradiation at MeV-range energies on live cells has been investigated at dose rates exceeding 109 Gy/s as a single exposure. A clonogenic assay showed consistent lethal effects on V-79 live cells, which, even at these dose rates, appear to be in line with previously published results employing conventional sources. A Relative Biological Effectiveness (RBE) of 1.4±0.2 at 10% survival is estimated from a comparison with a 225 kVp X-ray source.
Materialart:
Online-Ressource
ISSN:
2158-3226
Sprache:
Englisch
Verlag:
AIP Publishing
Publikationsdatum:
2012
ZDB Id:
2583909-3
