In:
Biomicrofluidics, AIP Publishing, Vol. 6, No. 3 ( 2012-09-01)
Abstract:
We demonstrate monolithic integration of fine cylindrical glass microcapillaries (diameter ∼1 μm) on silicon and evaluate their performance for electrophoretic separation of biomolecules. Such microcapillaries are achieved through thermal reflow of a glass layer on microstructured silicon whereby slender voids are moulded into cylindrical tubes. The process allows self-enclosed microcapillaries with a uniform profile. A simplified method is also described to integrate the microcapillaries with a sample-injection cross without the requirement of glass etching. The 10-mm-long microcapillaries sustain field intensities up to 90 kV/m and limit the temperature excursions due to Joule heating to a few degrees Celsius only.
Type of Medium:
Online Resource
ISSN:
1932-1058
Language:
English
Publisher:
AIP Publishing
Publication Date:
2012
detail.hit.zdb_id:
2265444-6
