In:
Journal of Physics: Conference Series, IOP Publishing, Vol. 2103, No. 1 ( 2021-11-01), p. 012053-
Abstract:
One of the promising approaches for diagnosing oncohematological diseases is infrared spectroscopy of blood serum. In this work secondary structure of blood serum proteins of patients with multiple myeloma, chronic lymphocytic leukemia and healthy donors was studied using IR spectroscopy. As a result of the study, it was found that the secondary structure of blood serum proteins in patients with chronic lymphocytic leukemia does not change in comparison with healthy donors. In contrast, patients with multiple myeloma have significant differences in the secondary structure composition of serum proteins compared to healthy donors. We conclude, that IR spectroscopy makes it possible to distinguish serum of healthy donors and patients with multiple myeloma, leading to the potential applicability of this approach to the diagnosis of multiple myeloma.
Type of Medium:
Online Resource
ISSN:
1742-6588
,
1742-6596
DOI:
10.1088/1742-6596/2103/1/012053
Language:
Unknown
Publisher:
IOP Publishing
Publication Date:
2021
detail.hit.zdb_id:
2166409-2
