In:
Aesthetic Surgery Journal, Oxford University Press (OUP), Vol. 43, No. 1 ( 2023-01-09), p. NP38-NP48
Kurzfassung:
Although botulinum toxin type A (BTX-A) injection has been proved to reduce topical sebum secretion, the impact of intradermal BTX-A injection on scalp sebum production has never been reported. Objectives The purpose of this study was to investigate the efficacy and safety of intradermal BTX-A treatment vs intradermal normal saline (NS) injection for scalp sebum secretion regulation. Methods This multicenter, randomized, double-blinded, prospective study recruited patients complaining of oily scalp and/or hair. The patients were randomly allocated to receive either 1 session of intradermal BTX-A or NS injection. The baseline and posttreatment scalp sebum secretion at 24, 48, 72, and 96 hours postshampooing was measured with a Sebumeter SM815 (Cutometer Dual MPA 580, Courage & Khazaka, Cologne, Germany) at 1, 3, 4, and 6 months after treatment. The patients’ comments, satisfaction, and adverse events were evaluated and compared. Results In total, 25 patients in the BTX-A group and 24 patients in the NS group completed the follow-up. For the treated region, compared with NS, intradermal BTX-A treatment (50-65 U) significantly reduced scalp sebum secretion at 24, 48, and 72 hours postshampooing at the 1- and 3-month follow-up visits (P & lt; 0.05). No significant difference between the 2 groups was observed at 4 and 6 months after the treatment. The patients’ satisfaction ratings were significantly higher for the BTX-A treatment (P = 0.000). No serious adverse events occurred. Conclusions Compared with NS, 1 session of intradermal BTX-A injection (50-65 U) effectively and safely reduced scalp sebum secretion and greasiness perception in the treated region at 24 and 48 hours postshampooing for 3 months. Level of Evidence: 4
Materialart:
Online-Ressource
ISSN:
1090-820X
,
1527-330X
Sprache:
Englisch
Verlag:
Oxford University Press (OUP)
Publikationsdatum:
2023
ZDB Id:
2048788-5
