KOBV Portal

Hits per page

hit 1 - 1 | 1 hit

Select All Export

Online Resource

Novel features and enhancements in BioBin, a tool for the biologically inspired binning and association analysis of rare variants

Basile, Anna O ; Byrska-Bishop, Marta ; Wallace, John ; [et al.]

Oxford University Press (OUP) ; 2018

In: Bioinformatics Vol. 34, No. 3 ( 2018-02-01), p. 527-529

add to watchlist on the watchlist

Details

In: Bioinformatics, Oxford University Press (OUP), Vol. 34, No. 3 ( 2018-02-01), p. 527-529

Abstract: BioBin is an automated bioinformatics tool for the multi-level biological binning of sequence variants. Herein, we present a significant update to BioBin which expands the software to facilitate a comprehensive rare variant analysis and incorporates novel features and analysis enhancements. Results In BioBin 2.3, we extend our software tool by implementing statistical association testing, updating the binning algorithm, as well as incorporating novel analysis features providing for a robust, highly customizable, and unified rare variant analysis tool. Availability and implementation The BioBin software package is open source and freely available to users at http://www.ritchielab.com/software/biobin-download Supplementary information Supplementary data are available at Bioinformatics online.

Type of Medium: Online Resource

ISSN: 1367-4803 , 1367-4811

URL: Article

DOI: 10.1093/bioinformatics/btx559

Language: English

Publisher: Oxford University Press (OUP)

Publication Date: 2018

detail.hit.zdb_id: 1468345-3

SSG: 12