In:
Biology of Reproduction, Oxford University Press (OUP), ( 2024-01-15)
Kurzfassung:
Histones post-translational modifications (PTMs), such as phosphorylation, methylation, acetylation and ubiquitination, play vital roles in various chromatin-based cellular processes. Meiosis is crucial for organisms that depend on sexual reproduction to produce haploid gametes, during which chromatin undergoes intricate conformational changes. An increasing body of evidence is clarifying the essential roles of histone PTMs during meiotic divisions. In this review, we concentrate on the PTMs of H2A, H2B, H3 and H4 as well as the linker histone H1 that are required for meiosis and summarize recent progress in understanding how these modifications influence diverse meiotic events. Finally, challenges and exciting open questions for future research in this field are discussed.
Materialart:
Online-Ressource
ISSN:
0006-3363
,
1529-7268
DOI:
10.1093/biolre/ioae011
Sprache:
Englisch
Verlag:
Oxford University Press (OUP)
Publikationsdatum:
2024
ZDB Id:
1469812-2
SSG:
12
