In:
The Journal of Infectious Diseases, Oxford University Press (OUP), Vol. 226, No. 10 ( 2022-11-11), p. 1721-1725
Kurzfassung:
To determine viral dynamics in Omicron breakthrough infections, we measured severe acute respiratory syndrome coronavirus 2 RNA in 206 double-vaccinated or boostered individuals. During the first 3 days following the onset of symptoms, viral loads were significantly higher (cycle threshold [Ct], 21.76) in vaccinated compared to boostered (Ct, 23.14) individuals (P = .029). However, by performing a longitudinal analysis on 32 individuals over 14 days, no difference in the viral load trajectory was observed between double-vaccinated and boostered patients. Our results indicate that booster immunization results in a reduction in detectable viral loads without significantly changing viral load dynamics over time.
Materialart:
Online-Ressource
ISSN:
0022-1899
,
1537-6613
DOI:
10.1093/infdis/jiac290
Sprache:
Englisch
Verlag:
Oxford University Press (OUP)
Publikationsdatum:
2022
ZDB Id:
1473843-0
