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  • 1
    In: JNCI Cancer Spectrum, Oxford University Press (OUP)
    Abstract: Cognitive problems contribute to decline in work performance. We evaluated (1) the effectiveness of basic self-management and extensive therapist-guided online cognitive rehabilitation on attainment of individually predetermined work-related goals among occupationally active cancer survivors, and (2) whether effectiveness of the programs differed for survivors with and without formal cognitive impairment. Methods In a three-armed randomized controlled trial (NCT03900806), 279 non-central nervous system cancer survivors with cognitive complaints were assigned to the basic program (n = 93), the extensive program (n = 93), or a waiting-list control group (n = 93). Participants completed measurements pre-randomization (T0), 12 weeks post-randomization upon program completion (T1), and 26 weeks post- randomization (T2). Mixed-effects modeling was used to compare intervention groups with the control group on goal attainment, and on self-perceived cognitive problems, work ability, and health-related quality of life. Results Participants in the extensive program achieved their predetermined goals better than controls, at short- and long-term follow-up (Effect Size (ES)=.49; p & lt;.001; ES=.34; p=.014). They also had less recovery needs after work (ES=-.21; p=.011), more vitality (ES=.20; p=.018), and better physical role functioning (ES=.0.43 p=.015) than controls. At long-term follow-up, this finding persisted for physical role functioning (ES=.42; p=.034). The basic program elicited a small positive non-significant short-term (not long-term) effect on goal attainment for those with adequate adherence (ES=.28, p=.053). Effectiveness of the programs did not differ for patients with or without cognitive impairment. Conclusions Internet-based therapist-guided extensive cognitive rehabilitation improves work-related goal attainment. Considering the prevalence of cognitive problems in survivors, it is desirable to implement this program.
    Type of Medium: Online Resource
    ISSN: 2515-5091
    Language: English
    Publisher: Oxford University Press (OUP)
    Publication Date: 2024
    detail.hit.zdb_id: 2975772-1
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