In:
Journal of Glaucoma, Ovid Technologies (Wolters Kluwer Health), Vol. 26, No. 2 ( 2017-02), p. 138-143
Abstract:
To compare the lamina cribrosa (LC) intensity in glaucoma-suspect eyes and eyes with mild to moderate glaucoma using swept-source optical coherence tomography. Methods: Optic disc volume scans were collected using swept-source optical coherence tomography in 19 clinically defined glaucoma-suspect eyes and 29 eyes with mild to moderate glaucoma. LC intensity was measured using Image J software, and the resultant values were normalized using the retinal pigment epithelium and vitreous signal. Results: Mean age was 53.7±18.5 years in the glaucoma-suspect eyes and 63.0±16.1 years in the eyes with mild to moderate glaucoma ( P =0.161). Significant differences in LC intensity were observed between the 2 groups, with median LC intensity values of 0.96 and 0.86 units in the glaucoma-suspect and the mild to moderate glaucoma groups, respectively ( P 〈 0.001). A weak positive correlation was found between mean deviation and normalized LC intensity ( r =0.344; P =0.018). Conclusions: Intensity measurement of the LC is a potential novel parameter which warrants further study in the setting of glaucoma.
Type of Medium:
Online Resource
ISSN:
1057-0829
DOI:
10.1097/IJG.0000000000000605
Language:
English
Publisher:
Ovid Technologies (Wolters Kluwer Health)
Publication Date:
2017
detail.hit.zdb_id:
2060541-9
