In:
Annals of Plastic Surgery, Ovid Technologies (Wolters Kluwer Health), Vol. 84, No. 1S ( 2020-1), p. S7-S10
Abstract:
Pulmonary complications are common among patients who have undergone major oral cancer surgery with microvascular reconstruction. Current literatures focused on early-onset pneumonia in the postoperative acute stage. In contrast, we are aiming to identify the clinical importance and the risk factors associated with late-onset pneumonia in oral cancer patients after acute stage. Methods In total, 195 patients were included from May 2014 to December 2016 and followed up for up to 1 year after surgery. Their medical histories were reviewed to identify the risk factors of late-onset pneumonia and outcome. Primary outcome was late-onset pneumonia. Other outcome measures included early-onset pneumonia, tumor recurrence, and death within 1 year after surgery. Results Patients with late-onset pneumonia have demonstrated a significantly higher rate of tumor recurrence ( P 〈 0.001) and death within 1 year ( P 〈 0.001). Independent risk factors of late-onset pneumonia identified were age ( P = 0.031), previous radiotherapy ( P = 0.017), postoperative radiotherapy ( P = 0.002), flap size ( P = 0.001), flap type other than osteocutaneous fibula flap ( P = 0.009), and tumor recurrence ( P 〈 0.001). Conclusions Late-onset pneumonia can act as a warning sign for oral cancer patients who have received microsurgical reconstruction, for its high correlation with tumor recurrence and mortality rate.
Type of Medium:
Online Resource
ISSN:
1536-3708
,
0148-7043
DOI:
10.1097/SAP.0000000000002170
Language:
English
Publisher:
Ovid Technologies (Wolters Kluwer Health)
Publication Date:
2020
detail.hit.zdb_id:
2063013-X
