In:
International Clinical Psychopharmacology, Ovid Technologies (Wolters Kluwer Health), Vol. 38, No. 3 ( 2023-05), p. 192-194
Abstract:
Benzodiazepines are used in the treatmentof anxiety and insomnia. On the other hand, they not only have side effects such as drowsiness, poor concentration, and muscle relaxation but also persistent cognitive decline. Even if we try to reduce the dose of these drugs to improve drug-induced cognitive function, it is difficult to do so due to dependence and worsening insomnia. I report four cases in which cognitive dysfunction was improved by switching from benzodiazepines to orexin receptor antagonists (suvorexant and lemborexant ). Orexin receptor antagonists were effective to improve cognitive impairment. In cognitive dysfunction caused by benzodiazepines, switching to orexin receptor antagonists may be effective.
Type of Medium:
Online Resource
ISSN:
0268-1315
DOI:
10.1097/YIC.0000000000000450
Language:
English
Publisher:
Ovid Technologies (Wolters Kluwer Health)
Publication Date:
2023
detail.hit.zdb_id:
1500677-3
SSG:
15,3
