In:
Journal of Medical Microbiology, Microbiology Society, Vol. 57, No. 5 ( 2008-05-01), p. 658-663
Kurzfassung:
Leptospirosis is a zoonotic disease with global distribution, caused by spirochaetes of the genus Leptospira . Transmission of Leptospira interrogans serovar Icterohaemorrhagiae, the causative agent of Weil's disease, to humans usually results from exposure to the urine of infected, but mostly asymptomatic, rodents, either by direct contact or indirectly through contaminated soil or water. Although regarded as a re-emerging infectious disease, human leptospirosis is probably underdiagnosed due to its often unspecific clinical appearance and difficulties in culturing leptospires. Therefore, more rapid and specific diagnostic procedures are needed. Here we describe a novel real-time quantitative PCR system developed for the accurate and fast diagnosis of pathogenic Leptospira spp. Its usefulness in the management of a patient with rat bite-associated multiorgan failure is demonstrated.
Materialart:
Online-Ressource
ISSN:
0022-2615
,
1473-5644
DOI:
10.1099/jmm.0.47677-0
Sprache:
Englisch
Verlag:
Microbiology Society
Publikationsdatum:
2008
ZDB Id:
2083944-3
SSG:
12
