In:
Genes & Development, Cold Spring Harbor Laboratory, Vol. 27, No. 10 ( 2013-05-15), p. 1073-1078
Abstract:
The abundant RNA-binding proteins CsrA and Hfq each impact bacterial physiology by working in conjunction with small RNAs to control large post-transcriptional regulons. The small RNAs involved were considered mechanistically distinct, regulating mRNAs either directly through Hfq-mediated base-pairing or indirectly by sequestering the global translational repressor CsrA. In this issue of Genes & Development , Jørgensen and colleagues (pp. 1132–1145) blur these distinctions with a dual-mechanism small RNA that acts through both Hfq and CsrA to regulate the formation of bacterial biofilms.
Type of Medium:
Online Resource
ISSN:
0890-9369
,
1549-5477
DOI:
10.1101/gad.220178.113
Language:
English
Publisher:
Cold Spring Harbor Laboratory
Publication Date:
2013
detail.hit.zdb_id:
1467414-2
SSG:
12
