In:
Journal of Synchrotron Radiation, International Union of Crystallography (IUCr), Vol. 22, No. 5 ( 2015-09-01), p. 1263-1267
Kurzfassung:
The objective of this study was to investigate the potential of hydrogen peroxide-generated oxygen gas-based phase contrast imaging (PCI) for visualizing mouse hepatic portal veins. The O 2 gas was made from the reaction between H 2 O 2 and catalase. The gas production was imaged by PCI in real time. The H 2 O 2 was injected into the enteric cavity of the lower sigmoid colon to produce O 2 in the submucosal venous plexus. The generated O 2 gas could be finally drained into hepatic portal veins. Absorption contrast imaging (ACI) and PCI of O 2 -filled portal veins were performed and compared. PCI offers high resolution and real-time visualization of the O 2 gas production. Compared with O 2 -based ACI, O 2 -based PCI significantly enhanced the revealing of the portal vein in vivo . It is concluded that O 2 -based PCI is a novel and promising imaging modality for future studies of portal venous disorders in mice models.
Materialart:
Online-Ressource
ISSN:
1600-5775
DOI:
10.1107/S1600577515010103
DOI:
10.1107/S1600577515010103/mo5112sup1.mov
Sprache:
Unbekannt
Verlag:
International Union of Crystallography (IUCr)
Publikationsdatum:
2015
ZDB Id:
2021413-3
