In:
Acta Crystallographica Section E Crystallographic Communications, International Union of Crystallography (IUCr), Vol. 78, No. 5 ( 2022-05-01), p. 468-472
Abstract:
A new pseudopolymorph of berberine, 9,10-dimethoxy-5,6-dihydro-2 H -7λ 5 -[1,3]dioxolo[4,5- g ]isoquinolino[3,2- a ]isoquinolin-7-ylium chloride methanol monosolvate, C 20 H 18 NO 4 + ·Cl − ·CH 3 OH, was obtained during co-crystallization of berberine chloride with malonic acid from methanol. The berberine cations form dimers, which are further packed in stacks. The title structure was compared with other reported solvates of berberine chloride: its dihydrate, tetrahydrate, and ethanol solvate hemihydrate. Hirshfeld analysis was performed to show the intermolecular interactions in the crystal structure of the title compound, and its fingerprint plots were compared with those of the already studied solvates.
Type of Medium:
Online Resource
ISSN:
2056-9890
DOI:
10.1107/S2056989022003309
DOI:
10.1107/S2056989022003309/yk2164sup1.cif
DOI:
10.1107/S2056989022003309/yk2164Isup3.hkl
DOI:
10.1107/S2056989022003309/yk2164Isup3.cml
Language:
Unknown
Publisher:
International Union of Crystallography (IUCr)
Publication Date:
2022
detail.hit.zdb_id:
2843762-7
detail.hit.zdb_id:
2041947-8