In:
Journal of Food Science, Wiley, Vol. 81, No. 7 ( 2016-07)
Abstract:
We investigated the effects of the polysaccharide from the sporophyll of a selected brown alga Undaria pinnatifida on serum lipid profile, fat tissue accumulation, and gastrointestinal transit time in rats fed a high‐fat diet. The algal polysaccharide (AP) was prepared by the treatment of multiple cellulase‐producing fungi Trichoderma reesei and obtained from the sporophyll with a yield of 38.7% (dry basis). The AP was mostly composed of alginate and fucoidan (up to 89%) in a ratio of 3.75:1. The AP was added to the high‐fat diet in concentrations of 0.6% and 1.7% and was given to male Sprague–Dawley rats (5‐wk‐old) for 5 wk. The 1.7% AP addition notably reduced body weight gain and fat tissue accumulation, and it improved the serum lipid profile, including triglycerides, total cholesterol, and very low‐density lipoprotein‐cholesterol. The effects were associated with increased feces weight and shortened gastrointestinal transit time. In addition, the lipid peroxidation of the liver was decreased in both groups.
Type of Medium:
Online Resource
ISSN:
0022-1147
,
1750-3841
DOI:
10.1111/jfds.2016.81.issue-7
DOI:
10.1111/1750-3841.13335
Language:
English
Publisher:
Wiley
Publication Date:
2016
detail.hit.zdb_id:
2006705-7