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    Online Resource
    Online Resource
    Wiley ; 2013
    In:  Journal of Medical Imaging and Radiation Oncology Vol. 57, No. 6 ( 2013-12), p. 680-683
    In: Journal of Medical Imaging and Radiation Oncology, Wiley, Vol. 57, No. 6 ( 2013-12), p. 680-683
    Abstract: Gallium‐68 ( 68 Ga )‐labelled somatostatin analogue imaging by positron emission tomography ( PET ) is increasingly replacing single photon (such as 111 I n‐labelled octreotide) imaging in the detection and staging of carcinoid and other neuroendocrine tumours. Among other tissues, pituitary uptake of 1,4,7,10‐tetraazacyclododecane‐1,4,7,10‐tetraacetic acid‐octreotate ( DOTA‐TATE ) and other somatostatin analogues is physiological. DOTA‐TATE also accumulates in meningiomas, which have a high density of somatostatin receptor expression. The combination of pituitary and skull base meningioma uptake results in a characteristic ‘double hot spot’ appearance, which indicates the presence of a meningioma. This is a case of a middle‐aged woman who underwent 68 Ga ‐ DOTA‐TATE PET for confirmation and staging of clinically suspected carcinoid tumour, in whom a skull base meningioma was incidentally discovered. With the increasing use of PET in the management of neuroendocrine tumours – and the not infrequent occurrence of meningiomas – the appearance of meningiomas on somatostatin analogue imaging should be one with which reporting clinicians are familiar.
    Type of Medium: Online Resource
    ISSN: 1754-9477 , 1754-9485
    URL: Issue
    Language: English
    Publisher: Wiley
    Publication Date: 2013
    detail.hit.zdb_id: 2409071-2
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