In:
Environmental Microbiology Reports, Wiley, Vol. 8, No. 2 ( 2016-04), p. 227-234
Abstract:
Bacterial populations differentiate at the subspecies level into clonal complexes. Intraclonal genome diversity was studied in 100 isolates of the two dominant P seudomonas aeruginosa clones C and PA 14 collected from the inanimate environment, acute and chronic infections. The core genome was highly conserved among clone members with a median pairwise within‐clone single nucleotide sequence diversity of 8 × 10 −6 for clone C and 2 × 10 −5 for clone PA 14. The composition of the accessory genome was, on the other hand, as variable within the clone as between unrelated clones. Each strain carried a large cargo of unique genes. The two dominant worldwide distributed P . aeruginosa clones combine an almost invariant core with the flexible gain and loss of genetic elements that spread by horizontal transfer.
Type of Medium:
Online Resource
ISSN:
1758-2229
,
1758-2229
DOI:
10.1111/emi4.2016.8.issue-2
DOI:
10.1111/1758-2229.12372
Language:
English
Publisher:
Wiley
Publication Date:
2016
detail.hit.zdb_id:
2485218-1
