In:
Australian Endodontic Journal, Wiley, Vol. 47, No. 2 ( 2021-08), p. 314-319
Kurzfassung:
The absence or presence of root resorption on the root surface of a replanted tooth indicates an immune‐inflammatory reaction. Since interleukin‐6 (IL‐6) is considered an inflammatory marker in bone resorption, this study aimed to investigate the association between clinical variables and polymorphisms in IL6 , with the outcome of replanted teeth at 1‐year follow‐up. Altogether, 127 avulsed teeth that were replanted and had their root canals treated were selected for this study. Periapical radiographs were taken after replantation and after 1 year. Real‐time PCR was used to genotype IL6 polymorphisms. Chi‐square and ‘ Z ’ tests were performed to verify the association between genetic variables and the prognosis of replanted teeth ( P 〈 0.05). An association was observed between the rs2069843 polymorphism of IL6 and the outcome of replanted teeth ( P 〈 0.05). The rs2069843 polymorphism of IL6 may influence the outcome of avulsed and replanted teeth in the first year post‐trauma.
Materialart:
Online-Ressource
ISSN:
1329-1947
,
1747-4477
Sprache:
Englisch
Verlag:
Wiley
Publikationsdatum:
2021
ZDB Id:
2208451-4
