In:
Acta Paediatrica, Wiley, Vol. 106, No. 5 ( 2017-05), p. 763-767
Kurzfassung:
Milk banks are advised to use Holder pasteurisation to inactivate the cytomegalovirus, but the process adversely affects the bioactive properties of human breastmilk. This study explored the antibacterial efficacy of an alternative high‐temperature short‐time ( HTST ) treatment of human breastmilk and its effect on marker proteins, compared with the Holder method. Methods Breastmilk samples were obtained from 27 mothers with infants in a German neonatal intensive care unit. The samples were either heated to 62°C for five seconds using HTST or processed using Holder pasteurisation, at 63 ± 0.5°C for 30 minutes. Immunoglobulin A, lactoferrin, lysozyme, alkaline phosphatase and bile salt‐stimulated lipase concentrations and bacterial colony‐forming units/mL were measured before and after heating. Results HTST ‐treated samples retained higher rates of immunoglobulin A (95% versus 83%), alkaline phosphatase (6% versus 0%) and bile salt‐stimulated lipase (0.8% versus 0.4%) than Holder pasteurisation samples (all p 〈 0.01), but not lactoferrin (32% versus 20%, p = 0.18) and lysozyme (72% versus 65%, p = 1). No difference in antibacterial efficacy was noted between the two groups (p = 0.29). Conclusion Using the HTST treatment protocol retained some of the bioactive properties of human breastmilk and appeared to have similar antibacterial efficacy to Holder pasteurisation.
Materialart:
Online-Ressource
ISSN:
0803-5253
,
1651-2227
DOI:
10.1111/apa.2017.106.issue-5
Sprache:
Englisch
Verlag:
Wiley
Publikationsdatum:
2017
ZDB Id:
1492629-5
ZDB Id:
1501466-6
