In:
Chemical Biology & Drug Design, Wiley, Vol. 89, No. 1 ( 2017-01), p. 61-66
Abstract:
Enzymatic glycosylation of sterols/steroids with glycosyltransferase HP 0421 shows protein plasticity on generation of configurationally rare steryl‐α‐glucosides. Investigation of trans ‐androsteronyl‐α‐glucoside on tamoxifen‐treated MCF ‐7 breast cancer cells shows dose‐dependent depression of cell viability and enhanced drug effectiveness, illustrating a new avenue for the production of novel steryl‐α‐glucosides with useful biological activities.
Type of Medium:
Online Resource
ISSN:
1747-0277
,
1747-0285
DOI:
10.1111/cbdd.2017.89.issue-1
Language:
English
Publisher:
Wiley
Publication Date:
2017
detail.hit.zdb_id:
2216600-2
SSG:
12
