In:
Digestive Endoscopy, Wiley, Vol. 30, No. 4 ( 2018-07), p. 461-466
Abstract:
The role of capsule endoscopy ( CE ) in established celiac disease ( CD ) remains unclear. Our objective was to analyze the usefulness of CE in the suspicion of complicated CD . Methods This was a retrospective multicenter study. One hundred and eighty‐nine celiac patients (mean age: 46.6 ± 16.6, 30.2% males) who underwent CE for alarm symptoms ( n = 86, 45.5%) or non‐responsive CD ( n = 103, 54.5%) were included. Diagnostic yield ( DY ), therapeutic impact and safety were analyzed. Results Capsule endoscopy was completed in 95.2% of patients (small bowel transit time: 270.5 ± 100.2 min). Global DY was 67.2%, detecting atrophic mucosa ( n = 92, 48.7%), ulcerative jejunoileitis ( n = 21, 11.1%), intestinal lymphoma ( n = 7, 3.7%) and other enteropathies ( n = 7, 3.7%, six Crohn's disease cases and one neuroendocrine tumor). The DY of CE was significantly higher in patients presenting with non‐responsive disease compared to patients with alarm symptoms (73.8% vs 59.3%, P = 0.035). The new findings of the CE modified management in 59.3% of the cases. There were no major complications. Conclusion Capsule endoscopy may be a moderately helpful and safe diagnostic tool in the suspicion of complicated CD , modifying the clinical course of these patients.
Type of Medium:
Online Resource
ISSN:
0915-5635
,
1443-1661
DOI:
10.1111/den.2018.30.issue-4
Language:
English
Publisher:
Wiley
Publication Date:
2018
detail.hit.zdb_id:
2020071-7