In:
Diabetic Medicine, Wiley, Vol. 36, No. 5 ( 2019-05), p. 620-625
Abstract:
Insulin resistance complicates the management of Type 1 diabetes. Accumulation of glycation end products reflects long‐term, chronic management of diabetes better than a single HbA 1c value and can be measured non‐invasively by skin autofluorescence. Advanced glycation end product accumulation in the skin is correlated to insulin resistance in Type 1 diabetes. The relationship is two‐way. Insulin sensitivity is associated with less accumulation of advanced glycation end products in the skin. An elevated level of advanced glycation end products increases the likelihood of insulin resistance by more than four times.
Type of Medium:
Online Resource
ISSN:
0742-3071
,
1464-5491
DOI:
10.1111/dme.2019.36.issue-5
Language:
English
Publisher:
Wiley
Publication Date:
2019
detail.hit.zdb_id:
2019647-7