In:
International Journal of Immunogenetics, Wiley, Vol. 46, No. 1 ( 2019-02), p. 1-6
Abstract:
Geographical distribution of ABO and RHD antigens is important for blood transfusion services and population genetics studies. There are few data on this topic in Burkina Faso, a multi‐ethnic country. Our study aims at reporting phenotypic and allelic frequencies of ABO and RHD blood groups among voluntary blood donors from various ethnical regions of Burkina Faso. We conducted a cross‐sectional study including 81,486 blood donors. ABO allelic frequencies were determined using the Bernstein method. Differences in phenotypic distribution of blood groups were assessed using the chi‐square test; a p value 〈 0.05 being considered as statistically significant. We noticed that O+ 〉 B+ 〉 A+ 〉 AB+ 〉 O‐ 〉 B‐ 〉 A‐ 〉 AB‐ in our population. Phenotypic frequencies of blood groups A, B, O and AB were respectively 22.54%, 28.56%, 43.30% and 5.60%. RHD+was 92.24%. The allelic frequencies of A, B, O and D were respectively 0.1524; 0.1887; 0.6590 and 0.7214. We noticed statistical differences ( p 〈 0.05) between these administrative regions which corresponded roughly to some natural ethnic areas. Indeed, the phenotype O was more frequent in the Central‐west, Central and East regions corresponding to “Mossi,” “Gourounsi,” “Gourmantché” areas while the phenotype A and AB were more reported in “Boucle du mouhoun” and “Hauts‐Bassins” regions where we have “Bwaba” and “Bobo.” The phenotype O negative was less frequent in “Bwaba.” Our study provides interesting information to blood services that will allow them to better refine their donor recruitment strategies.
Type of Medium:
Online Resource
ISSN:
1744-3121
,
1744-313X
DOI:
10.1111/iji.2019.46.issue-1
Language:
English
Publisher:
Wiley
Publication Date:
2019
detail.hit.zdb_id:
2179530-7
SSG:
12
