In:
European Journal of Neurology, Wiley, Vol. 14, No. 7 ( 2007-07), p. 815-818
Abstract:
Amyotrophic lateral sclerosis (ALS) may be accompanied by cognitive impairment; when present, it is mainly in the form of frontotemporal impairment. We report on two cases with clinically defined ALS that subsequently developed dementia. Neuropathological examination showed not only the typical neuropathological hallmarks characteristic of ALS but, surprisingly, also showed neurofibrillary tangles and neuritic plaques in sufficient numbers to fulfill the diagnostic criteria of definite Alzheimer's disease.
Type of Medium:
Online Resource
ISSN:
1351-5101
,
1468-1331
DOI:
10.1111/ene.2007.14.issue-7
DOI:
10.1111/j.1468-1331.2007.01759.x
Language:
English
Publisher:
Wiley
Publication Date:
2007
detail.hit.zdb_id:
2020241-6