In:
Journal of Gastroenterology and Hepatology, Wiley, Vol. 31, No. 4 ( 2016-04), p. 808-813
Kurzfassung:
CO 2 has been reported to be absorbed from the bowel more rapidly than air, resulting in a discomfort reduction after colonoscopy. Its role in deeply sedated patients is limited. This study was designed to investigate the efficacy and safety of CO 2 insufflation during colonoscopy in patients deeply sedated with propofol. Methods: A total of 125 continuous patients were randomly assigned to receive either CO 2 ( n = 63) or air ( n = 62) insufflation during propofol‐sedated colonoscopy. Postcolonoscopy abdominal pain, distention, and satisfaction were assessed at 1, 3, and 24 h after the procedure, and the proportions of pain‐free and distention‐free patients were compared. Residual bowel gas in the colon and small bowel was evaluated at 1 h after colonoscopy. End‐tidal CO 2 and O 2 saturation was measured for safety analysis. Results: There was a significant difference between the two groups regarding the postcolonoscopy abdominal pain, distention, and subjective satisfaction at 1 h ( P 〈 0.001) and 3 h ( P 〈 0.01) after the procedure. Patients' pain and distention at 1 and 3 h after the procedure were significantly lower in the CO 2 group ( P 〈 0.01). Residual bowel gas in the colon and small bowel was significantly less in the CO 2 group ( P 〈 0.001). There was no significant difference in end‐tidal CO 2 levels between two groups before, during, and after the procedure. Conclusions: Compared with air, CO 2 insufflation during colonoscopy reduced postcolonoscopy abdominal discomfort and improved patients' satisfaction. It was safe to use CO 2 insufflation in deeply sedated colonoscopy.
Materialart:
Online-Ressource
ISSN:
0815-9319
,
1440-1746
DOI:
10.1111/jgh.2016.31.issue-4
Sprache:
Englisch
Verlag:
Wiley
Publikationsdatum:
2016
ZDB Id:
2006782-3
