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    In: Journal of Interventional Cardiology, Wiley, Vol. 27, No. 2 ( 2014-04), p. 171-176
    Kurzfassung: We tried to determine the effect of stent balloon inflation time on stent expansion and apposition using optical coherence tomography . Background Second‐generation drug‐eluting stents (DES) have thin struts; however, inflation times for optimal stent expansion and apposition are unknown in vivo . Methods Subjects included 17 patients (18 de novo coronary artery lesions), in whom Resolute Integrity → (n = 9) and Xience Prime → (n = 9) DES were deployed. All stents were inflated 3 times to the nominal inflation pressure (8.9 ± 0.6 atm) using the stent delivery balloon. The first inflation continued until the stent was angiographically fully expanded; the other 2 lasted 15 and 30 seconds, respectively . Results After the first, second, and third inflation of stent balloon, stent area (5.94 ± 1.7, 6.69 ± 1.8, 7.05 ± 1.8 mm 2 , P  〈  0.001) and stent volume (146.94 ± 59.40, 166.78 ± 69.55, 177.25 ± 69.19 mm 3 , P  〈  0.001) increased significantly. The number of malapposed struts (18.0 ± 17.0, 7.9 ± 10.2, 7.4 ± 10.8, P  〈  0.001) and the mean depth of malapposed struts (188.9 ± 75.6, 120.3 ± 101.4, 95.4 ± 86.8 µm, P  〈  0.001) decreased. Malapposed stent area (0.62 ± 0.32, 0.52 ± 0.21 mm 2 , P  〈  0.05) and the malapposed stent volume (15.03 ± 7.78, 12.64 ± 5.16 mm 3 , P  〈  0.05) decreased significantly following the second inflation; the third inflation gave no additional benefits to these parameters. There was no adverse clinical outcome after each stent balloon inflation . Conclusions Additional 15 seconds of inflation after the angiographically full expansion of the stent balloon allows better stent expansion and apposition even though the inflation pressure is nominal pressure . (J Interven Cardiol 2014;27:171–176)
    Materialart: Online-Ressource
    ISSN: 0896-4327 , 1540-8183
    URL: Issue
    Sprache: Englisch
    Verlag: Wiley
    Publikationsdatum: 2014
    ZDB Id: 2103585-4
    Bibliothek Standort Signatur Band/Heft/Jahr Verfügbarkeit
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