In:
Journal of Oral Rehabilitation, Wiley, Vol. 45, No. 4 ( 2018-04), p. 289-294
Abstract:
The synovial membrane and fluid are significantly involved in the pathogenesis of temporomandibular joint ( TMJ ) disorders. This study aimed to investigate the relation between levels of chemerin in the synovial fluid ( SF ) of patients with TMJ disorder and their relationship. Sixty samples of SF were obtained from patients with an internal derangement ( ID ) or osteoarthritis ( OA ). Chemerin in the SF was examined by enzyme‐linked immunosorbent assay ( ELISA ). The results showed greater levels of chemerin in the SF of patients with OA than ID . While chemerin levels were positively correlated with pain scores, they were inversely correlated with MMO . Chemerin levels increased progressively as the disorder stage became more severe. The findings of this study suggest that chemerin in SF may play role as a predisposing factor and may represent a novel potential prognostic biochemical marker in the pathogenesis of TMJ disorders.
Type of Medium:
Online Resource
ISSN:
0305-182X
,
1365-2842
DOI:
10.1111/joor.2018.45.issue-4
Language:
English
Publisher:
Wiley
Publication Date:
2018
detail.hit.zdb_id:
2007587-X