In:
Photochemistry and Photobiology, Wiley, Vol. 94, No. 4 ( 2018-07), p. 752-759
Abstract:
The systematic review and meta‐analysis were undertaken to evaluate the effectiveness of antimicrobial photodynamic therapy ( aPDT ) in the microbiological alteration beneficial to peri‐implantitis treatment. This study is registered with PROSPERO , number CRD 42017064215. Bibliographic databases including Cochrane Library, Web of Science, Scopus and PubMed were searched from inception to 8 January 2017. The search strategy was assembled from the following MeSH Terms: “Photochemotherapy,” “Dental Implants” and “Peri‐Implantitis.” Unspecific free‐text words and related terms were also included. The Cochrane Collaboration's tool was used to evaluate the risk of bias of included studies. The random‐effect model was chosen, and heterogeneity was evaluated using the I 2 test. Three studies met the inclusion criteria. Meta‐analysis demonstrated an association between aPDT and reduction in viable bacteria counts for: Aggregatibacter actinomycetemcomitans ( OR = 1.31; confidence interval = 1.13, 1.49; P 〈 0.00001), Porphyromonas gingivalis ( OR = 4.08; confidence interval = 3.22, 4.94; P 〈 0.00001) and Prevotella intermedia ( OR = 1.66; confidence interval = 1.06, 2.26; P 〈 0.00001). A aPDT appears to be effective in bacterial load reduction in peri‐implantitis and has a positive potential as an alternative therapy for peri‐implantitis.
Type of Medium:
Online Resource
ISSN:
0031-8655
,
1751-1097
DOI:
10.1111/php.2018.94.issue-4
Language:
English
Publisher:
Wiley
Publication Date:
2018
detail.hit.zdb_id:
2048860-9
SSG:
12