In:
Transfusion, Wiley, Vol. 61, No. 1 ( 2021-01), p. 159-166
Abstract:
Although Hematopoietic Stem Cells (HSC) donation through bone marrow (BM) and peripheral blood (PB) are usually safe procedures, adverse events are expected. One of the most common events especially among BM donors (BMD) is the development of anemia. To protect the BMD and preserve the hemoglobin levels, many centers collect autologous pre‐procedure blood, but the actual benefits of this procedure is controversial. Methods and Materials This study analyzed retrospectively data to observe what factors may influence the occurrence of post‐donation anemia and also evaluate the relevance of autologous red blood cell pre procedure donation (PAD). Results The development of immediately post donation anemia (IP) was higher in BMD than in PB donors (64.2% BMD and 10.7% PBD, P 〈 .001) and also in late post donation (LP) (28.4% BMD and 3.6% PBD, P = .007). The study demonstrated an association between PAD and anemia in IP (72.7% with anemia and 27.3% without anemia, P = .006) and an association between the volume of red blood cells in the donated hematopoietic product and the development of anemia in LP (356.3 mL and 297.8 mL, P = .037). Conclusion In conclusion, collection of HSC through BM is a risk factor for anemia and PAD is a risk factor for IP anemia.
Type of Medium:
Online Resource
ISSN:
0041-1132
,
1537-2995
Language:
English
Publisher:
Wiley
Publication Date:
2021
detail.hit.zdb_id:
2018415-3
