In:
Veterinary Dermatology, Wiley, Vol. 29, No. 3 ( 2018-06), p. 222-
Abstract:
Background – Total IgE concentrations in dogs are higher than in humans. Persistent Toxocara canis larval infestation is prevalent in dogs and is associated with substantial specific antibody reactions. A correlation, however, between total IgE and T. canis ‐specific antibody levels in dogs has not been evaluated. Objectives – To determine the relationship between total IgE, T. canis ‐specific IgG and IgE, and allergen‐specific IgE levels in atopic and non‐atopic dogs, and to evaluate possible confounding factors. Conclusions – Toxocara canis ‐specific IgE appears to be a major component of total IgE in dogs. Total and T. canis ‐specific IgE levels are higher in non‐atopic compared to atopic dogs. It is speculated that T. canis infestation may have a protective effect against the development of canine atopic dermatitis and/or that elevations in total serum IgE level are often not associated with atopic dermatitis.
Type of Medium:
Online Resource
ISSN:
0959-4493
,
1365-3164
DOI:
10.1111/vde.2018.29.issue-3
Language:
English
Publisher:
Wiley
Publication Date:
2018
detail.hit.zdb_id:
2011122-8
SSG:
22